PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G46830.1
Common NameATNIG1, BHLH28, EN40, MZA15.1, NIG1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 511aa    MW: 57348 Da    PI: 6.0145
Description NACL-inducible gene 1
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G46830.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH37.15.8e-12343388454
                  HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                  +h e+Er RR+++N++f  Lr ++P+       K++K + Le Av YI++L
  AT5G46830.1 343 NHVEAERMRREKLNHRFYALRAVVPNV-----SKMDKTSLLEDAVCYINEL 388
                  799***********************6.....5***************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142152.1E-4435225IPR025610Transcription factor MYC/MYB N-terminal
CDDcd000835.55E-13338389No hitNo description
SuperFamilySSF474593.14E-16339408IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.399339388IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000103.2E-9343388IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.107.6E-15343409IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.3E-13345394IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042538Biological Processhyperosmotic salinity response
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005509Molecular Functioncalcium ion binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0008019anatomyleaf lamina base
PO:0009006anatomyshoot system
Sequence ? help Back to Top
Protein Sequence    Length: 511 aa     Download sequence    Send to blast
MINTDDNLLM IEALLTSDPS PPLLPANLSL ETTLPKRLHA VLNGTHEPWS YAIFWKPSYD  60
DFSGEAVLKW GDGVYTGGNE EKTRGRLRRK KTILSSPEEK ERRSNVIREL NLMISGEAFP  120
VVEDDVSDDD DVEVTDMEWF FLVSMTWSFG NGSGLAGKAF ASYNPVLVTG SDLIYGSGCD  180
RAKQGGDVGL QTILCIPSHN GVLELASTEE IRPNSDLFNR IRFLFGGSKY FSGAPNSNSE  240
LFPFQLESSC SSTVTGNPNP SPVYLQNRYN LNFSTSSSTL ARAPCGDVLS FGENVKQSFE  300
NRNPNTYSDQ IQNVVPHATV MLEKKKGKKR GRKPAHGRDK PLNHVEAERM RREKLNHRFY  360
ALRAVVPNVS KMDKTSLLED AVCYINELKS KAENVELEKH AIEIQFNELK EIAGQRNAIP  420
SVCKYEEKAS EMMKIEVKIM ESDDAMVRVE SRKDHHPGAR LMNALMDLEL EVNHASISVM  480
NDLMIQQANV KMGLRIYKQE ELRDLLMSKI S
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A1e-41312256192Transcription factor MYC3
4rqw_B1e-41312256192Transcription factor MYC3
4rs9_A1e-41312256192Transcription factor MYC3
4yz6_A1e-41312256192Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1324332KKGKKRGRK
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible248867_at0.0
Expression AtlasAT5G46830-
AtGenExpressAT5G46830-
ATTED-IIAT5G46830-
Functional Description ? help Back to Top
Source Description
TAIRCalcium-binding transcription factor involved in salt stress signaling.
Function -- GeneRIF ? help Back to Top
  1. MYC5, probably together with other, redundant transcription factors, may be activated by JA signaling to induce the expression of MYB21 and components required for male fertility.
    [PMID: 25627909]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00547DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G46830.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By UV treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Interaction ? help Back to Top
Source Intact With
BioGRIDAT5G60890, AT5G61420, AT1G18570, AT1G74080
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G46830
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0222210.0AB022221.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone:MSD23.
GenBankAF2526360.0AF252636.1 Arabidopsis thaliana putative transcription factor bHLH28 mRNA, complete cds.
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_199495.10.0calcium-binding transcription factor NIG1
SwissprotQ9LUK70.0BH028_ARATH; Transcription factor bHLH28
TrEMBLC0SVS80.0C0SVS8_ARATH; Putative uncharacterized protein At5g46830 (Fragment)
STRINGAT5G46830.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM139531624
Representative plantOGRP37331224
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Day IS,Reddy VS,Shad Ali G,Reddy AS
    Analysis of EF-hand-containing proteins in Arabidopsis.
    Genome Biol., 2002. 3(10): p. RESEARCH0056
    [PMID:12372144]
  3. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  4. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  7. Lorenzo O,Chico JM,S
    JASMONATE-INSENSITIVE1 encodes a MYC transcription factor essential to discriminate between different jasmonate-regulated defense responses in Arabidopsis.
    Plant Cell, 2004. 16(7): p. 1938-50
    [PMID:15208388]
  8. Kim J,Kim HY
    Functional analysis of a calcium-binding transcription factor involved in plant salt stress signaling.
    FEBS Lett., 2006. 580(22): p. 5251-6
    [PMID:16962584]
  9. Tominaga-Wada R,Iwata M,Nukumizu Y,Wada T
    Analysis of IIId, IIIe and IVa group basic-helix-loop-helix proteins expressed in Arabidopsis root epidermis.
    Plant Sci., 2011. 181(4): p. 471-8
    [PMID:21889054]
  10. Frerigmann H,Berger B,Gigolashvili T
    bHLH05 is an interaction partner of MYB51 and a novel regulator of glucosinolate biosynthesis in Arabidopsis.
    Plant Physiol., 2014. 166(1): p. 349-69
    [PMID:25049362]
  11. Figueroa P,Browse J
    Male sterility in Arabidopsis induced by overexpression of a MYC5-SRDX chimeric repressor.
    Plant J., 2015. 81(6): p. 849-60
    [PMID:25627909]
  12. Qi T,Huang H,Song S,Xie D
    Regulation of Jasmonate-Mediated Stamen Development and Seed Production by a bHLH-MYB Complex in Arabidopsis.
    Plant Cell, 2015. 27(6): p. 1620-33
    [PMID:26002869]